How does Acomplia work?

• Acomplia acts by selectively blocking CB1 receptors found in the brain and in peripheral organs important in glucose and lipid (or fat) metabolism, including adipose tissue, the liver, gastrointestinal tract and muscle1
• Acomplia switches off the same brain circuits that make people hungry when they smoke cannabis
• CB1 receptor blockade with Acomplia acts to decrease the overactivity of the endocannabinoid system (EC system)2,3. The EC system is a recently characterised physiological system that includes receptors such as the CB1 receptor and it has been shown to play an important role in regulating body weight and in controlling energy balance, as well as glucose and lipid (or fat) metabolism.

What is Acomplia used for?

• Acomplia is used complementary to diet and exercise to treat obese or overweight patients who suffer from Type 2 diabetes and abnormal levels of fat in the blood
• Acomplia can also prevent the risk of cardiovascular disease
• Patients with large waist circumference (102 cm in men and 88 cm in women) will mostly benefit from taking the drug.

Does Acomplia also aid smoking cessation?

Clinical trials have shown that heavy smokers, after being on a regular supplement of Acomplia, have stopped smoking altogether. Smokers usually do not stop smoking for fear of weight-gain, which can be highly discouraging. However since Acomplia works on the overeating and smoking factors simultaneously such problems wouldn't arise.